Crystal structure of 1-[2-[6-(4-methoxyphenyl)-3(2H)-pyridazinone- 2-yl]-acetyl]-4-(3-chlorophenyl)piperazine, C23H23ClN4O3
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چکیده
منابع مشابه
Crystal structures of 2-acetyl-4-ethynylphenol and 2-acetyl-4-(3-hydroxy-3-methylbut-1-yn-1-yl)phenol
In the title compounds, C10H8O2, (I), and C13H14O3, (II), the 2-acetyl-4-ethynylphenol unit displays a planar geometry, which is stabilized by an intra-molecular O-H⋯O hydrogen bond. The crystal structure of (I) is constructed of infinite strands, along [101], of C-H⋯O=C hydrogen-bonded mol-ecules, which in turn are linked by C-H⋯π inter-actions. In the crystal of (II), which crystallized with ...
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In the title compound, C20H26ClNO4, the central cyclo-hexene ring adopts an approximate envelope conformation with the C atom binding with the hy-droxy group at the tip of the flap. There is an intramolecular N-H⋯O hydrogen bond generating an S(6) ring motif. In the crystal, classical O-H⋯O hydrogen bonds and weak C-H⋯O and C-H⋯Cl inter-actions link the mol-ecules, forming a three-dimensional s...
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A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...
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A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...
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In the title compound, C27H19N3O, the dihedral angles between the plane of the pyridine ring and those of the indole (r.m.s. deviation = 0.018 Å), phenyl and meth-oxy-benzene substituents are 33.60 (6), 25.28 (7) and 49.31 (7)°, respectively. The N atom of the carbo-nitrile group is significantly displaced [0.288 (2) Å] from the plane of the pyridine ring, perhaps due to steric crowding. In the...
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ژورنال
عنوان ژورنال: Zeitschrift für Kristallographie - New Crystal Structures
سال: 2000
ISSN: 2197-4578,1433-7266
DOI: 10.1515/ncrs-2000-0362